Esparza will defend her title against Joanna Jedrzejczyk, who earned a split decision victory vs. Claudia Gadelha last December just days after Esparza won the inaugural title.
Jedrzejczyk (8-0) is 2-0 with the UFC, having also scored a decision over Juliana Lima. Of her eight career wins, three have been finishes.
Esparza (10-2) came over to the UFC after winning the Invicta FC strawweight title vs. Bec Rawlings in 2013. She earned a submission win over Rose Namajunas in the TUF finals and is on a five-fight win streak.
UPDATE: The bout was confirmed for the co-main event slot during “UFC Tonight” Wednesday evening.
Below is the current lineup:
UFC Lightweight Championship
Anthony Pettis (c) vs. Rafael dos Anjos
UFC Female Strawweight Championship
Carla Esparza (c) vs. Joanna Jedrzejczyk
Heavyweight: Alistair Overeem vs. Roy Nelson
Flyweight: Chris Cariaso vs. Henry Cejudo
Welterweight: Johny Hendricks vs. Matt Brown
Middleweight: Elias Theodorou vs. Roger Narvaez
Flyweight: Sergio Pettis vs. Ryan Benoit