Virgil Zwicker, who was scheduled to face Lorenz Larkin in the main event of Strikeforce Challengers 19, has been forced to pull out of the planned fight, according to officials.
Strikeforce also announced on Tuesday that Jerron Peoples has been injured and will not be able to compete in his planned prelim match with Joe Ray.
The card is set for September 23 from the Palms Casino and Resort in Las Vegas, Nevada.
Replacements for both injured fighters are expected to be announced shortly.
Other planned bouts for the main card include Ryan Couture facing Maka Watson, Lavar Johnson facing Shawn Jordan, Jason High taking on Todd Moore and Brian Melancon meeting Felipe Portela.